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About
Prothena Corp. Plc is a clinical stage biotechnology company, which engages in the discovery, development, and commercialization of novel antibodies. Its antibody-based product candidates target a number of potential indications including AL amyloidosis (NEOD001), Parkinson's disease and related synucleinopathies (PRX002), inflammatory diseases including psoriasis, psoriatic arthritis (PRX003), and ATTR amyloidosis (PRX004). The company was founded on December 20, 2012 and is headquartered in Dun Laoghaire, Ireland. | |||
Description
Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on the discovery, development, and commercialization of novel immunotherapies for the treatment of diseases that involve protein misfolding or cell adhesion. It is developing antibody-based product candidates that include NEOD001, a monoclonal antibody that is in Phase III and Phase IIb clinical trials for the treatment of AL amyloidosis; PRX002 that has completed Phase Ib clinical trial for treating Parkinson's disease and other related synucleinopathies; PRX003, a monoclonal antibody that is in Phase Ib for the treatment of psoriasis and other inflammatory diseases; and PRX004, a monoclonal antibody that is under preclinical development. The company has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein. Prothena Corporation plc was incorporated in 2012 and is headquartered in Dun Laoghaire, Ireland. |